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Lumbar Transforaminal ESI
Selective Nerve Block













Overview and Indications for transforaminal steroid injections

Lumbar transforaminal steroid injections (With X-ray Guidance) are used to reduce pain, improve function and enable patient to pursue physical Therapy /Rehabilitation and return to work, sports and daily /leisure activities. Its main indication is to decrease the inflammation associated with a variety of spinal conditions, such as herniated disc, sciatica, spinal stenosis, degenerative disc disease with nerve root impingement. There seems to be a better response when the injections are coupled with an organized therapeutic exercise program, activity modification and ergonomic corrections.

Risk Associated with transforaminal steroid injections


It is important to know risks are associated with any medical or surgical treatment. There are a few risks associated with Lumbar epidural steroid injections and they tend to be rare.


The potential risk includes:


  • Immediate or delayed ALLERGIC reaction to medication use

  • Infection

  • Bleeding

  • Nerve or spinal cord Injury

  • Dural Puncture

  • Temporary increase in pain

  • High blood sugar levels

  • Transient vaginal spotting

  • Transient facial flushing

  • Spinal vascular injury or vascular uptake of a particular steroid


Infection rate is less than 1% in patients receiving spinal injections performed under sterile conditions. The bleeding complication is more common in patients with history of bleeding disorder, patients being treated with anticoagulant/antiplatelet medications and patients taking over the counter medication like Motrin and Aspirin. The frequency of injury to the nerve roots or spinal cord has been substantially reduced with use of fluoroscopy and contrast material. It is rare to encounter nerve root or spinal cord injury with epidural injections. The rate of nerve injury and spinal cord injury is higher in obese patients due to poor visualization of the target on lateral X-rays. Dural puncture is an infrequent complication and may cause a positional headache (headache in seated and standing position but not on laying down position). This type of headache is often self-limiting, although in persistent cases, a blood patch may be necessary to alleviate the headache. Elevated blood sugar is a known effect of steroid medication and may last for 2-4 days after the injection of steroids. Patients on insulin will be following sliding scale to adjust for elevated sugar levels. Patients on oral medication should follow primary care advice regarding temporary increase in oral medication to accommodate for blood sugar levels.

The following side effects tend to be rare, though they become more common when steroids are taken daily for several months. These risks and side effects may include:


  • A transient decrease in immunity

  • Stomach ulcers

  • Severe arthritis of the hips (avascular necrosis)

  • Cataracts

  • Increased appetite

  • Agitation and irritability

  • Negative effect on bone density and fractures

Who should avoid transforaminal epidural steroid injections?


Lumbar Transforaminal Epidural Steroid Injections should not be performed on patients with the following conditions:


  • In individuals with known allergies to local anesthetics, steroids or contrast material

  • Patients with local or systemic bacterial infection

  • Pregnant patients

  • Patients with bleeding disorders

  • Patients suffering from a tumor or infection of the spine

  • Uncontrolled congestive heart failure or diabetes

  • When risk of holding certain mediations (Aspirin, antiplatelet drugs/blood thinners) outweighs benefit of the epidural procedure

Prepare for your transforaminal steroid injections

Certain medications have to be held before elective spinal procedures. A list of such medications is on the last few pages of this educational material. Do not hold such medication on your own. Ask your PCP or Cardiologist if it is safe to stop such medication before the procedure. Continue to take all other medications, especially your Blood Pressure and diabetes medications.


A sample of medications that must be held includes:


  1. Aggrenox® (dipyridamole)

  2. Aspirin

  3. Coumadin® (warfarin)

  4. Effient® (prasugrel)

  5. Fragmin® (dalteparin)

  6. NSAIDS (see sample below)

  7. Herbal blood-thinners

  8. Heparin

  9. Eliquis ® (apixaban)

  10. Lovenox® (enoxaparin)

  11. Plavix® (clopidogrel),

  12. Pradaxa® (dabigatran)

  13. Ticlid® (ticlopidine)


NSAIDS to be held (such as Ibuprofen, Motrin, Naproxen, Advil, Nabumetone, Diclofenac, Etodolac, Indomethacin, Ketorolac, Meloxicam, Piroxicam, Ketoprofen, Oxaprozin)


Please let us know if you have had fevers, antibiotic treatment, any illness, or hospitalization within the last 4 weeks. You must be healthy and off all antibiotics on the day of the procedure


Make sure you are not Pregnant at the time of procedure. Do a Urine Pregnancy Test the night before your spinal injection and report the results to the nurse before the procedure. Exposure to X-ray (used during spinal procedure) is known to result in birth defects and possible miscarriage. If in doubt, cancel and reschedule your procedure until you can confirm that you are not pregnant.

Day of your Procedure


  • Please take a shower, wash the skin with normal soap and DO NOT put skin lotions or mediated creams in the area of the injection.

  • Wear dark, loose clothing and undergarment.

  • Arrive 30 minutes early and come with someone that can give you a ride home. Your procedure should take less than 30 minutes and your total time from greeting to end should be less than 90 minutes.

  • Bring an updated list of your medications and allergies. Please point out if you are allergic to Contrast, Iodine or Latex.

  • Bring your latest MRI /CT /imaging studies and the report with you.

  • Do not eat or drink for 2 hours before your appointment. Diabetics may have a light meal.

  • After check-in, an ID wristband containing your name and allergies will be placed on your wrist. A nurse or medical assistant will go over your meds and allergies and ask few screening questions. Then a nurse will go over final preparation before the procedure. If necessary, an IV line will be placed particularly if this is your first spinal procedure.

  • In rare cases, oral sedation is needed to reduce anxiety associated with the procedure. This will slow down the entire process. Take medication 1 hour before the procedure and you must have someone drive you to and from the procedure. Without the ride, procedure would likely be canceled


During the Procedure 


  • You will change into a gown. You will be escorted to the procedure by a nurse and a consent form will be reviewed/ signed before the procedure. You will be asked to lay on your stomach

  • Blood pressure and heart rate monitor will be placed on your arm/finger. Every medical equipment produces loud noises (beeping, alarms) and you should not be concerned.

  • Intermittently your doctor will talk to staff in the procedure room and instruct them to perform a task. Your physician will guide you step by step through the procedure.

  • After standard time out, your skin will be disinfected with a cool solution, and sterile sheet of paper or plastic will be placed on your skin.

  • When your physician is ready, X-ray unit is placed over your spine to identify the target.

  • Skin will be marked and anesthetized (you will feel small pinch and burning sensation at each spot). It is normal to feel pressure or muscles twitching as needles are advanced to the final target.

  • Once needle is at radiographic target, a small amount of contrast is injected to confirm final needle position before injecting steroid medication. You may feel transient pressure in your spine.

  • Once procedure is completed, needle is removed, skin is cleaned and bandage is applied. You are then transferred back to the recovery area for observation.


Right after the Procedure


  • You will be observed for 15-45 minutes.

  • If you have an IV line, it will be removed.

  • A nurse will check your vitals and review the discharge instructions with you and will answer any questions you may have. A responsible adult must be present to drive you home after discharge.

  • You will leave along with a pain log and a copy of the discharge instruction which contains Emergency contact numbers. Please do not discard your discharge instructions.

  • A responsible adult must drive you home.


Discharge instructions for transforaminal steroid injections


  • Make a follow-up 2-3 weeks after the procedure and bring your pain log with you.

  • For 24 hours after the procedure, do not drive or operate machinery.

  • If sedated, for 24 hours after the procedure, do not make financial or important life decisions until the effect of such medication is cleared

  • For 24 hours after the procedure, do not participate in strenuous activity

  • It is okay to shower after the procedure. No bathing /submerging under the water for a day .

  • You may remove the bandages 24 hours after the injection. Call if there is excessive redness or infection sign like warmth, discharge, or collection of puss at the site of injection.

  • You may resume your normal diet and medications after the procedure.

  • Resume your Blood Thinners/ Anticoagulants / Antiplatelet as instructed by PCP /Cardiologist. You may need to check INR/PT/PTT 2-3 days after your procedure. Contact your primary care and ask when you should have the blood work.

  • Diabetics should monitor blood sugar levels 3 times a day for 3 days after the procedure.

Call your doctor if you develop these symptoms. You may be directed to ER:


  • Shortness of breath or palpitation after the procedure

  • Sudden weakness

  • Fever over 101°F within 5 days after the procedure

  • Persistent redness increased localized pain or discharge from the site of injection.

  • Possible allergic reaction within 5 days of the procedure

  • Intractable headache

  • Significant increased pain not responding to ice, NSAIDS and pain meds or associated with fever

  • Newly developed weakness in the legs, face or arm following procedure

  • Newly developed incontinence of urine or stool following procedure.

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INSURANCE  Coverage 


Most insurances require prior authorization to cover this procedure. It takes anywhere between 3-15 days for approval (Medicare beneficiaries require no authorization). Our office will provide information to the insurance company for approval.


You will likely have copays, coinsurance, and deductibles for this type of treatment. You will also receive two medical bills related to these types of treatments (Ambulatory SurgiCenter bill and Doctors bill). Please call your insurance company to understand your benefits. The codes used for these procedures are: CPT: 64483, 64484 and 77003


Keywords: Lumbar Transforaminal Epidural Injection, Selective spinal Nerve Block

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